speaker
Dr. Sebastijan Peljhan completed his PhD in theoretical physical chemistry at University of Ljubljana, Faculty of Chemistry and Chemical Technology and »Jožef Stefan« Institute, Ljubljana, Slovenia in 2012. He was awarded the »Maks Samec« award by University of Ljubljana for his outstanding contribution on atomistic modelling of corrosion processes, which were the research topic of his thesis. At the same time he joined application department of BIA Separations, where he was in charge of downstream processes and analytical method development of biomolecules on monolithic chromatographic supports. Currently, his main focus is development of process analytical technologies supported by advanced data manipulation used in upstream and downstream of biotechnological processes.
培训主题:introduction to monolith technology and PAT
part1: introduction
part2:convective interaction media monolithic columns
part3:plasmid purification on CIM monoliths
part4:HPLC frigerprinting approach for increased speed and flexibility of PAT
part5: applications
Case I: Separation of empty and full AAV capsid
Case II: AAV fermentation scale up
Case III: AAV fermentation progress
Case IV: AAV unit operations
Case V: Fingerprinting the Cohn I+II+III paste-batch to batch paste reproducibility
Case VI: MAb charge variant separation(displacement method)
Case VII: pDNA isolation & purification
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