不同方法区分PDAC和胰腺炎的ROC曲线,纵坐标为敏感度,横坐标为(1-特异性),ROC曲线越接近左上角,准确性越高,假阳性和假阴性的数量越少,曲线下面积为AUC值,均可判断出蓝色虚线代表的THBS2和CA19-9联合使用是准确性最高的
Zaret教授表示,THBS2的检测并不复杂,现有的技术完全能够解决,在他们的实验中,CA19-9和THBS2联合使用高度准确地识别出了PDAC的不同阶段,而且比现有的包括CA19-9在内的检测方法更好。接下来,他们将继续扩大实验样本量,并且广泛招募未经他们诊断的胰腺癌患者,进一步验证和完善这个检测方法,希望能够早日进入真正的临床使用[8]。
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