实验室简介
实验室Group Leader为Dr.
Yansheng Liu
，专长于质谱技术与蛋白质组学，于2005-2010年在上海生命科学研究院完成博士学位，2011年5月至今（2017年）在瑞士苏黎世联邦理工大学（ETH Zurich) Ruedi Aebersold 实验室进行博士后研究，将于2017年12月入职任美国耶鲁大学癌症研究所 (Yale Cancer Biology Institute) 助理教授 (Tenure Track Assistant Professor)，癌症蛋白质组学课题组长。
Dr. Yansheng Liu目前以第一作者及共同第一身份在
Cell, Nature Biotechnology, Nature Communications, Molecular Systems Biology, Cell Reports, Molecular & Cellular Proteomics
等杂志发表多篇论文，被广泛引用；并担任
Proteomics
编委,
Proteomics-Clinical Applications
编委，及Frontiers in Physiology副主编。
目前的研究兴趣
： 1) 数据非依赖型蛋白质组学 (DIA proteomics)； 2) 癌症及其耐药性中关键蛋白质降解与翻译后调控； 3) 基因组－蛋白质组关联研究。本课题组配备最新质谱系统 Orbitrap Fusion™ Lumos™ Tribrid™ (Thermo Fisher) 和 Xevo G2-XS System (Waters)，与瑞士，美国，澳大利亚，中国，德国，英国等多课题组有长期合作关系。
因尚未入职，更多信息请参考临时网站
https://www.yslproteomics.org
。
博士后基本要求
因课题需要招收两名博士后，欢迎已经和即将毕业的博士研究生应聘。
1. 生物信息与系统生物学方向：要求精通R语言与科学绘图，掌握Python 或 Java，对蛋白质组感兴趣。
2. 质谱技术与癌症蛋白质组方向：要求有较强的质谱独立操作与维护的经验，对Orbitrap类特别是Fusion和Lumos熟悉的优先，对生物学问题感兴趣。
理想入职时间为2018年初。薪酬按耶鲁大学的标准执行。
应聘
请将简历以及cover letter发到
[email protected]
和
[email protected]
. 如合适会进一步要求2-3封推荐信，并电话面试／面试。应聘材料予以保密。
更多具体要求与两个博士后分别的招聘信息参见英文版, 如下。
1. Postdoctoral Position in Bioinformatics and Systems Biology
（
Starting in January 2018 or later
）
Our research is dedicated to delineate mechanisms of proteomic and post-translational control in different tumor cell models and cancer patients. One major focus is the proteomic data mining and management, the genome-proteome association analysis and mutilayered data integration for studying human diseases such as cancer. Please see more details at https://www.yslproteomics.org/ for the introduction of the group.
We invite applications from PhD – MD/PhD scientists to join our laboratory. Candidate requirements include Ph.D or M.D./Ph.D. (already obtained or soon to be), a high degree of motivation in academic research, decent record of scientific accomplishments with publication(s) in peer-reviewed journals, and ability to work independently and as a team player with excellent communication and writing skills. Knowledge in bioinformatics and high-throughput data analysis (NOT necessary in Proteomics) is essential. Excellent experience in R programing, data visualization, strong experience in Perl or Python or Java etc. languages, and an open mind in learning Proteomics are desirable. The work experience in a Proteomics or a Systems Biology group is advantageous.
The research group is affiliated to The Yale Cancer Biology Institute (YCBI) which connects scientists from across Yale to study the common underlying causes of cancer. The research group is well equipped with the state-of-the-art mass spectrometers such as Orbitrap Fusion™ Lumos™ Tribrid™ (Thermo Fisher) and Xevo G2-XS System (Waters).
We offer excellent working conditions: a competitive salary, international working environment, and direct access to high quality, question driven proteomic data sets. First and co-first author publications on high impact journals can be expected. The position is full time for 2 years (yearly renewable contract) with possibility to prolongation and it is available from January 2018. Salaries are according to Yale scale.
2. Postdoctoral Position in Mass Spectrometry and Proteomics
（
Starting in January 2018 or later
）
Our research is dedicated to delineate mechanisms of proteomic and post-translational control in different tumor cell models and cancer patients. One major focus is the proteomic data generation using cutting edge mass spectrometry, such as data-independent acquisition (DIA) and proteomic methodology development. Please see more details at https://www.yslproteomics.org/ for the introduction of the group.
We invite applications from PhD – MD/PhD scientists to join our laboratory. Candidate requirements include Ph.D or M.D./Ph.D. (already obtained or soon to be), a high degree of motivation in academic research, decent record of scientific accomplishments with publication(s) in peer-reviewed journals, and ability to work independently and as a team player with excellent communication and writing skills. Knowledge in mass spectrometry is essential. Excellent experience in Proteomics, sample preparation, operating/ maintaining Orbitrap-type machines (especially Fusion or Fusion Lumos), and an open mind in learning DIA Proteomics are desirable. The work experience in a Proteomics lab or relevant industry is advantageous.
The research group is affiliated to The Yale Cancer Biology Institute (YCBI) which connects scientists from across Yale to study the common underlying causes of cancer. The research group is well equipped with the state-of-the-art mass spectrometers such as Orbitrap Fusion™ Lumos™ Tribrid™ (Thermo Fisher) and Xevo G2-XS System (Waters).
