《自然-生物技术》编辑部在5月9日附录中发表关于NgAgo基因编辑的最新关切，主体译文如下：
自然生物技术的编辑发表一篇关于本文的编辑关切，提醒读者关于原始结果的可重复性得有关的问题。目前，我们发表了三个科研小组试图重复韩春雨及其同事的原始论文中重点结果图片图4中的结果（http://dx.doi.org/10.1038/nbt.3753）。但是没有任何一个小组能够在任何位点或任何条件下观察到NgAgo的诱发的任何突变。不同组的作者最近也在Protein & Cell报道了类似的结果（10.1007 / s13238-016-0343-9）。
我们与作者联系，他们正在调查潜在缺乏重复性的原因。作者已经被告知这一声明。调查工作正在进行之中，韩春雨和沈啸同意编辑部发表这一关切。 Feng Gao, Feng Jiang和Yongqiang Wu 认为这个时候不适合发这一关切。
一旦这些调查完成，我们会及时的给读者们更新相关结果。
原文如下：
Addendum
Editorial Expression of Concern: DNA-guided genome editing using the
Natronobacterium gregoryi Argonaute
Feng Gao, Xiao Z Shen, Feng Jiang, Yongqiang Wu & Chunyu Han
Nat. Biotechnol. 34, 768–773 (2016); published online 2 May 2016; addendum published after print 28 November 2016
The editors of Nature Biotechnology are issuing an editorial expression of concern regarding this article to alert our readers to concerns regarding
the reproducibility of the original results. At this time, we are publishing the results of three groups (http://dx.doi.org/10.1038/nbt.3753) that
have tried to reproduce the results in the critical Figure 4 in the original paper by Han and colleagues,which demonstrates editing of endogenous
genomic loci in mammalian cells. None of the groups observed any induction of mutations by NgAgo at any of the loci or under any of the conditions
tested above the sensitivity of the assays used. Similar results have been recently reported by a different group of authors in Protein & Cell
(doi:10.1007/s13238-016-0343-9).
We are in contact with the authors, who are investigating potential causes for the lack of reproducibility. The authors have been informed of this
statement. While the investigations are ongoing, Chunyu Han and Xiao Z. Shen agree with this editorial expression of concern. Feng Gao, Feng Jiang
and Yongqiang Wu do not feel that it is appropriate at this time.
We will update our readers once these investigations are complete
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