Database name | Current URL | Brief description |
Annual updates |
DDBJ | http://www.ddbj.nig.ac.jp | All known nucleotide and protein sequences |
ENA | http://www.ebi.ac.uk/ena | All known nucleotide and protein sequences |
GenBank | https://www.ncbi.nlm.nih.gov/genbank/ | All known nucleotide and protein sequences |
Ensembl | http://www.ensembl.org/ | Annotated information on eukaryotic genomes |
Mouse Genome Database | http://www.informatics.jax.org | Mouse genome database |
UCSC Genome Browser | http://genome.ucsc.edu/ | A universal genome viewing and analysis platform |
UniProt | http://www.uniprot.org | A universal database of protein sequences (includes Swiss-Prot and TrEMBL) |
Regular updates |
ArrayExpress | http://www.ebi.ac.uk/arrayexpress | Array-based gene expression data |
BioCycd | http://biocyc.org/ | Pathway information for sequenced |
BioGRID | http://www.thebiogrid.org | Genetic and physical interactions in yeast, worm and fly |
BRENDA | http://www.brenda-enzymes.info | Enzyme names and biochemical properties |
CGD | http://www.candidagenome.org/ | Candida Genome Database |
CanSAR | http://cansar.icr.ac.uk | Cancer research and drug discovery resource |
CATH | http://www.cathdb.info | Protein domain structure database |
CAZy | http://www.cazy.org | Carbohydrate-Active enZymes database |
CDD | http://www.ncbi.nlm.nih.gov/cdd | Conserved Domain Database |
ChEBI | http://www.ebi.ac.uk/chebi | Chemical Entities of Biological Interest |
ChEMBL | https://www.ebi.ac.uk/chembldb | Interaction of drugs and compounds with their targets |
ChimerDB | http://ercsb.ewha.ac.kr/fusiongene | Chromosome translocations and gene fusions |
COG | http://www.ncbi.nlm.nih.gov/COG | Clusters of Orthologous Groups of proteins |
Comparative Toxicogenomics Database | http://ctdbase.org | A knowledgebase for curated chemical-gene-disease networks |
COSMIC | http://cancer.sanger.ac.uk | Catalogue of Somatic Mutations in Cancer |
CyanoBase | http://genome.microbedb.jp/cyanobase | Cyanobacterial genomes |
dbPTM | http://dbPTM.mbc.nctu.edu.tw/ | Post-translational modification of proteins |
DBTSS | http://dbtss.hgc.jp/ | Database of transcriptional start sites |
DEG | http://www.essentialgene.org | Database of essential genes |
DictyBase | http://dictybase.org | Model organism database for Dictyostelium discoideum |
DrugBank | http://www.drugbank.ca/ | Drug and drug target database |
EcoCyc | http://ecocyc.org/ | E. coli K12 genes, metabolic pathways, transporters, and gene regulation |
eggNOG | http://eggnog.embl.de/ | Evolutionary genealogy of genes:Non-supervised Orthologous Groups |
ELM | http://elm.eu.org/ | Eukaryotic Linear Motif: functional sites in eukaryotic proteins |
EMAGE | http://www.emouseatlas.org/emage/ | e-Mouse Atlas of Gene Expression |
ENCODE project at UCSC | http://genome.ucsc.edu/ENCODE | Encyclopedia of DNA Elements,functional elements in human genome |
EPD | http://epd.vital-it.ch | Eukaryotic Promoter Database |
EuPathD | http://eupathdb.org/ | Unified genome databases on eukaryotic pathogens (includes PlasmoDB, ToxoDB, ApiDB,TrichDB, TriTrypDB, GiardiaDB,etc.) |
Expression Atlas | http://www.ebi.ac.uk/gxa/ | Dene expression patterns deduced from microarray and RNA-seq data |
FANTOM | http://fantom.gsc.riken.jp/ | Functional annotation of mouse full-length cDNA clones |
FINDBase | http://www.findbase.org | Frequencies of INherited Disorders |
FlyBase | http://flybase.org/ | Drosophila sequences and genomic information |
FlyRNAi | http://flyrnai.org/ | Genome-wide RNAi analysis in Drosophila |
Gene3D | http://gene3d.biochem.ucl.ac.uk | Structural domain assignments for protein sequences |
Genenames | http://www.genenames.org/ | The HGNC human gene nomenclature database |
GenomeRNAi | http://www.genomernai.org | RNA interference data for human and Drosophila |
GEO | http://www.ncbi.nlm.nih.gov/geo/ | NCBI’s Gene Expression Omnibus |
GO | http://www.geneontology.org | Gene Ontology Database |
GOA | http://www.ebi.ac.uk/GOA | Gene Ontology annotations for proteins in UniProt |
GOLD | https://gold.jgi.doe.gov/ | Genomes online database: completed and ongoing genome projects |
GPCRdb | http://gpcrdb.org/ | Data and tools for studying G protein-coupled receptors |
Gramene | http://www.gramene.org | Comparative genomics of crops and model plant species |
GXD | http://www.informatics.jax.org/expression.shtml | Mouse Gene Expression Database |
HAMAP | http://hamap.expasy.org/ | High-quality Automated and Manual Annotation of Proteins |
HMDB | http://www.hmdb.ca | Human Metabolome Database |
IEDB | http://www.iedb.org/ | Immune Epitope Database |
IMG/M | http://img.jgi.doe.gov/m | JGI’s Integrated Microbial Genomics and Metagenomics |
IMGT | http://www.imgt.org | International ImMunoGeneTics database. |
InParanoid | http://InParanoid.sbc.su.se | Orthologous relationships between eukaryotic proteomes |
IntAct | http://www.ebi.ac.uk/intact/ | Protein–Protein INTerACTion data |
InterPro | http://www.ebi.ac.uk/interpro | Integrated resource of protein families, domains and functional sites |
IPD | http://www.ebi.ac.uk/ipd | Immuno Polymorphism database (includes IMGT/HLA) |
JASPAR | http://jaspar.genereg.net/ | PSSMs for transcription factor DNA-binding sites |
KEGG | http://www.genome.ad.jp/kegg | Kyoto Encyclopedia of Genes and Genomes: genes, proteins, pathways |
MEROPS | http://merops.sanger.ac.uk/ | Database of proteases (peptidases) |
MetaCyc | http://metacyc.org/ | Metabolic pathways and enzymes in various organisms |
miRBase | http://www.mirbase.org/ | MicroRNA sequences, names and predicted targets in animals |
miRGator | http://mirgator.kobic.re.kr | MicroRNA expression profiles and mRNA targets |
miRGen | http://www.microrna.gr/mirgen | MicroRNA promoters and transcription start sites |
miRTarBase | http://miRTarBase.mbc.nctu.edu.tw/ | Experimentally validated microRNA–target interactions |
MMDB | http://www.ncbi.nlm.nih.gov/Structure | Molecular Modeling Database of protein structures |
MODOMICS | http://genesilico.pl/modomics/ | RNA modification pathways |
Mouse Tumor Biology Database | http://tumor.informatics.jax.org/mtbwi/ | Mouse as a model system of human cancers |
neXtProt | https://www.nextprot.org/ | A database of human proteins |
NONCODE | http://noncode.org/ | A database of noncoding RNAs |
OMIM | http://www.omim.org | Online Mendelian inheritance in man: A catalog of human genetic and genomic disorders |
OrthoDB | http://www.orthodb.org | An hierarchical catalog of orthologous proteins |
PANTHER | http://www.pantherdb.org | Protein sequence evolution mapped to functions and pathways |
PATRIC | http://www.patricbrc.org | PathoSystems Resource Integration Center |
PDB | http://rcsb.org/pdb | Protein DataBank: All biological macromolecular structures |
PDBe | http://www.ebi.ac.uk/pdbe/ | Protein Databank in Europe |
PDBsum | http://www.ebi.ac.uk/pdbsum | Summaries and analyses of PDB structures |
Pfam | http://pfam.xfam.org | Protein families: Multiple sequence alignments and profile hidden Markov models of protein domains |
PHI-base | http://www4.rothamsted.bbsrc.ac.uk/phibase/ | Genes affecting fungal pathogen–host interactions |
PIR | http://pir.georgetown.edu/ | Protein Information Resource, part of UniProt |
PRIDE | http://www.ebi.ac.uk/pride/ | Proteomics peptide identification database |
PRINTS | http://www.bioinf.man.ac.uk/dbbrowser/PRINTS | Protein fingerprints, conserved motifs used to characterise a protein family |
Prosite | http://www.expasy.org/prosite | Biologically-significant protein patterns and profiles |
PubChem | http://pubchem.ncbi.nlm.nih.gov/ | Structures and biological activities of small organic molecules |
RGD | http://rgd.mcw.edu/ | Rat Genome Database |
RDP | http://rdp.cme.msu.edu | Ribosomal Database Project:Bacterial and archaeal 16S rRNA and fungal 28S rRNA sequences |
Reactome | http://www.reactome.org | A database of metabolic and signaling pathways |
REBASE | http://rebase.neb.com/rebase/ | Restriction enzyme database |
RefSeq | https://www.ncbi.nlm.nih.gov/refseq/ | NCBI Reference Sequence Database |
Rfam | http://rfam.xfam.org | RNA families with multiple sequence alignments |
SCOP | http://scop.mrc-lmb.cam.ac.uk/ | Structural Classification Of Proteins |
SGD | http://www.yeastgenome.org | Saccharomyces Genome Database |
SILVA | http://www.arb-silva.de/ | Aligned small- and large subunit rRNA sequences |
SIMAP | http://mips.gsf.de/simap/ | Similarity Matrix of Proteins |
SMART | http://smart.embl-heidelberg.de | Simple Modular Architecture Research Tool: signalling,extracellular and chromatin-associated protein domains |
STITCH | http://stitch-db.org/ | Search Tool for Interactions of Chemicals |
STRING | http://string.embl.de/ | Predicted functional associations between proteins |
SUPERFAMILY | http://supfam.org | Genome-wide identification of protein domains of known structure |
SWISS-MODEL | http://swissmodel.expasy.org/ | 3D models for proteins of unknown structure |
TAIR | http://www.arabidopsis.org/ | The Arabidopsis information resource |
TarBase | http://microrna.gr/tarbase | Database of experimentally supported microRNA targets |
TCDB | http://www.tcdb.org/ | Transporter protein classification database |
UCSC Cancer Genomics Browser | https://genome-cancer.ucsc.edu/ | Visualization of cancer genomic datasets |
VectorBase | https://www.vectorbase.org/ | Invertebrate vectors of human pathogens |
WormBase | http://www.wormbase.org | Community portal on all aspects of C. elegans biology |
XenBase | http://www.xenbase.org | Xenopus frog database |
YEASTRACT | http://www.yeastract.com | Transcriptional regulation in Saccharomyces cerevisiae |
ZFIN | http://zfin.org/ | Zebrafish information network |