德克斯大学健康科学中心圣安东尼奥分校Dr. Mingjiang Xu和芝加哥大学何川组招收联合博后

Postdoc Pos itions Focusing on the Roles of RNA m5C Regulation in Normal

and Malignant Hematopoiesis

Postdoctoral positions are available in the research laboratories of Dr. Mingjiang Xu (https://directory.uthscsa.edu/academics/profile/xum1) at University of Texas Health San Antonio and Dr. Chuan He ( https://he-group.uchicago.edu ) at University of Chicago. The candidate will carry collaborative projects between the Xu and the He labs to investigate the roles of RNA m 5 C in the regulation of hematopoietic stem/progenitor cell function and in the development of hematological malignancies. These studies will be the extension of a recent discovery by the He and Xu labs published in Nature

(https://www.nature.com/articles/s41586-024-07969-x). The candidate will define the impact of RNA m 5 C marks on the regulation of a diverse physiological and pathological processes including transcription, translation, aging and transformation, focusing on the hematopoietic system. The unique tools are ranging from m 5 C writers/erasers/reader modulations and m 5 C profiling to animal modeling and primary human sample testing.