Advanced 旗舰系列期刊：细胞与分子生物学高影响力文章合集

Targeting Ferroptosis: Modulation Mechanisms and Therapeutic Implications

靶向铁死亡：调控机制与治疗意义

Biomechanics in Cellular Dynamics

细胞动力学中的生物力学

The Dual Role of Extracellular Vesicles in Disease Dynamics and Therapy

细胞外囊泡在疾病动态与治疗中的双重作用

Advancing Complexity and Physiological Relevance of In Vitro Tissue Models

提升体外组织模型的复杂性与生理相关性

Advances in Targeted Protein Degradation

靶向蛋白降解的最新进展

Pharmacological Inhibition of Ferroptosis as a Therapeutic Target for Neurodegenerative Diseases and Strokes

药理学抑制铁死亡：神经退行性疾病与中风的治疗靶点

Targeted xCT-mediated Ferroptosis and Protumoral Polarization of Macrophages Is Effective against HCC and Enhances the Efficacy of the Anti-PD-1/L1 Response

靶向xCT介导的铁死亡及巨噬细胞促肿瘤极化：对肝细胞癌的有效性及其对抗PD-1/L1疗法的增强作用

Malic Enzyme 1 as a Novel Anti-Ferroptotic Regulator in Hepatic Ischemia/Reperfusion Injury

苹果酸酶1：肝脏缺血再灌注损伤中的新型抗铁死亡调节因子

Tryptophan Metabolism Acts as a New Anti-Ferroptotic Pathway to Mediate Tumor Growth

色氨酸代谢作为新型抗铁死亡通路调控肿瘤生长

Nanoparticles Synergize Ferroptosis and Cuproptosis to Potentiate Cancer Immunotherapy

纳米颗粒协同铁死亡与铜死亡增强癌症免疫治疗

Programming a Ferroptosis-to-Apoptosis Transition Landscape Revealed Ferroptosis Biomarkers and Repressors for Cancer Therapy

构建铁死亡至凋亡转变图谱揭示癌症治疗中的铁死亡生物标志物及抑制因子

BRCC36 Deubiquitinates HMGCR to Regulate the Interplay Between Ferroptosis and Pyroptosis

BRCC36 通过去泛素化 HMGCR 调控铁死亡与焦亡的相互作用

Protective Effect of Compound Tongluo Decoction on Brain Vascular Endothelial Cells after Ischemia-Reperfusion by Inhibition of Ferroptosis Through Regulating Nrf2/ARE/SLC7A11 Signaling Pathway

复方通络汤通过调控Nrf2/ARE/SLC7A11信号通路抑制铁死亡，对脑血管内皮细胞缺血再灌注损伤具有保护作用

Ferroptosis in Glaucoma: A Promising Avenue for Therapy

铁死亡在青光眼中的作用：潜在的治疗新途径

Ferroptosis: A New Strategy for the Treatment of Fibrotic Diseases

铁死亡：治疗纤维化疾病的新策略

Static and Dynamic: Evolving Biomaterial Mechanical Properties to Control Cellular Mechanotransduction

静态与动态：调控细胞力传导的生物材料力学性能演变

Dynamic Stimulations with Bioengineered Extracellular Matrix-Mimicking Hydrogels for Mechano Cell Reprogramming and Therapy

利用仿生细胞外基质的生物工程水凝胶进行动态刺激，实现细胞力学重编程与治疗

Curved Nanofiber Network Induces Cellular Bridge Formation to Promote Stem Cell Mechanotransduction

弯曲纳米纤维网络诱导细胞桥形成，促进干细胞力传导

Defined Microenvironments Trigger In Vitro Gastrulation in Human Pluripotent Stem Cells

特定微环境触发人类多能干细胞的体外原肠胚形成

Hypertensive Pressure Mechanosensing Alone Triggers Lipid Droplet Accumulation and Transdifferentiation of Vascular Smooth Muscle Cells to Foam Cells

高血压压力机械感知单独触发脂滴积累并诱导血管平滑肌细胞向泡沫细胞转分化

Targeting Nuclear Mechanics Mitigates the Fibroblast Invasiveness in Pathological Dermal Scars Induced by Matrix Stiffening

靶向核力学调控缓解基质僵硬诱导的病理性皮肤瘢痕成纤维细胞侵袭性

Tumor Biomechanics Alters Metastatic Dissemination of Triple Negative Breast Cancer via Rewiring Fatty Acid Metabolism

肿瘤生物力学通过重塑脂肪酸代谢改变三阴性乳腺癌的转移扩散

Different Biomechanical Cell Behaviors in an Epithelium Drive Collective Epithelial Cell Extrusion

上皮细胞不同的生物力学行为驱动集体性细胞挤出

3D Micropatterned Traction Force Microscopy: A Technique to Control 3D Cell Shape While Measuring Cell-Substrate Force Transmission

3D微图案牵引力显微技术：在测量细胞-基质力传递的同时控制细胞三维形态

High-Throughput Multiparametric Quantification of Mechanics Driven Heterogeneity in Mesenchymal Stromal Cell Population

高通量多参数定量分析力学驱动的间充质基质细胞群体异质性

Lipid Nanoparticles Deliver the Therapeutic VEGFA mRNA In Vitro and In Vivo and Transform Extracellular Vesicles for Their Functional Extensions

脂质纳米颗粒体内外递送治疗性VEGFA mRNA并改造细胞外囊泡以拓展其功能

Inflammatory Fibroblast-Like Synoviocyte-Derived Exosomes Aggravate Osteoarthritis via Enhancing Macrophage Glycolysis

炎性成纤维样滑膜细胞来源的外泌体通过增强巨噬细胞糖酵解加重骨关节炎

Extracellular Vesicular Analysis of Glypican 1 mRNA and Protein for Pancreatic Cancer Diagnosis and Prognosis

细胞外囊泡中Glypican 1 mRNA和蛋白的分析用于胰腺癌的诊断与预后评估

High-Performance Hydrogel-Encapsulated Engineered Exosomes for Supporting Endoplasmic Reticulum Homeostasis and Boosting Diabetic Bone Regeneration

高性能水凝胶包裹工程化外泌体维持内质网稳态并促进糖尿病骨再生

Microfluidic Biochips for Single Cell Isolation and Single Cell Analysis of Multiomics and Exosomes

微流控生物芯片用于单细胞分离及多组学与外泌体的单细胞分析

Extracellular Vesicles from Highly Metastatic Osteosarcoma Cells Induce Pro-Tumorigenic Macrophage Phenotypes

高转移性骨肉瘤细胞来源的细胞外囊泡诱导促肿瘤巨噬细胞表型

Closer to The Heart: Harnessing the Power of Targeted Extracellular Vesicle Therapies

贴近心脏：靶向细胞外囊泡疗法的潜能开发

Impact of Isolation Methods on Extracellular Vesicle Functionality In Vitro and In Vivo

分离方法对细胞外囊泡体内外功能性的影响

3D In Vitro Blood-Brain-Barrier Model for Investigating Barrier Insults

用于研究屏障损伤的三维体外血脑屏障模型

Micro-Engineered Organoid-on-a-Chip Based on Mesenchymal Stromal Cells to Predict Immunotherapy Responses of HCC Patients

基于间充质基质细胞的微工程类器官芯片用于预测肝细胞癌患者的免疫治疗反应

A T Cell-Engaging Tumor Organoid Platform for Pancreatic Cancer Immunotherapy

一种T细胞介导的肿瘤类器官平台用于胰腺癌免疫治疗

Chronotoxici-Plate Containing Droplet-Engineered Rhythmic Liver Organoids for Drug Toxicity Evaluation

Chronotoxici-Plate：包含液滴工程化节律性肝类器官的药物毒性评估平台

Modeling the Effects of Protracted Cosmic Radiation in a Human Organ-on-Chip Platform

基于人体器官芯片平台模拟长期宇宙辐射的影响

Recent Progress in Generation of Inner Ear Organoid

内耳类器官生成的最新进展

In Vitro Models of Blood and Lymphatic Vessels-Connecting Tissues and Immunity

体外血管与淋巴管连接组织及免疫的模型研究

Essential Role of Anisotropy in Bioengineered Cardiac Tissue Models

生物工程化心脏组织模型中各向异性的重要作用

Microphysiological Models of Lung Epithelium-Alveolar Macrophage Co-Cultures to Study Chronic Lung Disease

肺上皮-肺泡巨噬细胞共培养的微生理模型用于研究慢性肺部疾病

Special Issue: Microphysiological Systems for Precision Medicine

特刊：精准医学中的微生理系统

Glutathione-Scavenging Nanoparticle-Mediated PROTACs Delivery for Targeted Protein Degradation and Amplified Antitumor Effects