专栏名称: 译言
发现、翻译、分享中文之外的互联网精华
目录
相关文章推荐
51好读  ›  专栏  ›  译言

科学家成功“编辑”了人类DNA,我们可以自己改造命运了吗?

译言  · 公众号  · 国际  · 2017-08-11 13:47

正文

一个美国科学团队和韩国的科学家们成功地“编辑”了人类DNA,打开了未来拯救生命医学治疗和伦理问题的大门。

科学家首次成功“编辑”人类DNA

Scientists Successfully ‘Edit’ Human DNA for the First Time

译者:leon921269  原文作者:Emma Niles


A team of U.S. and South Korean scientists have successfully “edited” human DNA, opening the door to future life-saving medical treatments as well as ethical questions.

一个美国科学团队和韩国的科学家们成功地“编辑”了人类DNA,打开了未来拯救生命医学治疗和伦理问题的大门。


According to the BBC, the scientists “successfully freed embryos of a piece of faulty DNA that causes deadly heart disease to run in families,” a process that “opens the door to preventing 10,000 disorders that are passed down the generations.”

据英国广播公司(BBC)报道,科学家们“成功修正了一份有缺陷DNA的胚胎,这种缺陷DNA可导致致命心脏疾病在家族中流行”,这一成功“为阻止代代相传的上万种疾病打开了一扇门。”


The BBC continues:

英国广播公司继续报道说:


US teams at Oregon Health and Science University and the Salk Institute along with the Institute for Basic Science in South Korea focused on hypertrophic cardiomyopathy.

美国俄勒冈健康科学大学和索尔克研究所的美国团队以及韩国基础科学研究所致力于肥厚性心肌病的研究。


The disorder is common, affecting one in every 500 people, and can lead to the heart suddenly stopping beating.

这种疾病很常见,每500人中就有一个人受其影响,并可能导致心脏突然停止跳动。


It is caused by an error in a single gene (an instruction in the DNA), and anyone carrying it has a 50-50 chance of passing it on to their children.

它是由单个基因(DNA中的一条指令)中的某个错误引起的,任何携带这种基因的人都有50%的机会将其传给自己的孩子。


In the study, described in the journal Nature, the genetic repair happened during conception.

在《自然》杂志上描述的这项研究中,基因修复是在怀孕期间进行的。


Sperm from a man with hypertrophic cardiomyopathy was injected into healthy donated eggs alongside Crispr technology to correct the defect.

一名患有肥厚性心肌病男子的精子被注射到健康的捐赠卵子中,并通过Crispr技术(基因编辑技术)来纠正这一缺陷。


It did not work all the time, but 72% of embryos were free from disease-causing mutations.

这一过程并不总是成功,但72%的胚胎没有出现致病突变。


However, this is not about to become routine practice.

然而,这并不一定成为常规做法。


The biggest question is one of safety, and that can be answered only by far more extensive research.

最大的问题是安全问题,只有更广泛的研究才能解答这个问题。


There are also questions about when it would be worth doing – embryos can already be screened for disease through pre-implantation genetic diagnosis.







请到「今天看啥」查看全文


推荐文章
晚安少年  ·  VOL.619 我想找个慢热型的爱人
8 年前
孔明湿兄  ·  32F蒙古乳神王李丹妮④
7 年前
城乡建设一PPP  ·  PPP操作中几个关键问题的解决思考
7 年前
天津大学图书馆  ·  图图有话说|| 一大波志愿者正在来袭!
7 年前