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癫痫发作后脑信号改变

影像学园  · 公众号  · 医学  · 2018-06-13 20:52

正文

【双语病例】Postictal Signal Changes 癫痫发作后脑信号改变

来自:双语学影像;本期病例选自AJNR Case of the Week

Pedram Parva, MD;Clinical Instructor in Radiology;Harvard Medical School;VA Hospital and Healthcare System;Boston, MA

Description

A 35-year-old man with change in mental status following seizures

35岁男性,癫痫发作后精神异常。

Axial DWI:


T2 GRE:


axial FLAIR:


One-week follow-up T2-FLAIR:


Legends

Axial DWI (A), T2 GRE (B), and axial FLAIR (C) R sequences demonstrate bilateral symmetric hippocampal restricted diffusion with no signs of hemorrhage and associated increased T2 signal and mild swelling. One-week follow-up T2-weighted FLAIR MR sequence (D) demonstrates resolution of the T2W signal abnormality.

横断位DWI、T2 GRE、FLAIR序列示:双侧海马区对称性弥散受限,未见明显出血灶,T2WI见海马区轻度水肿、呈稍高信号。

1周后复查,T2-FLAIR序列示海马区异常信号消失。


Postictal Signal Changes

癫痫发作后脑信号改变


Key Diagnostic Features
  • CT: transient focal decreased gyral or hippocampal attenuation

    CT:海马或脑回一过性密度减低。

  • MRI: transient increased signal on FLAIR and T2WI (most common in the frontal and parietal lobes but also seen in the temporal and occipital lobes)

    MRI:T2WI及FLAIR一过性信号增高(常见于额、顶叶,也可见于颞叶和枕叶)

  • Reversible diffusion restriction and abnormal cortical enhancement has been reported.

    有文献报道,病灶弥散受限,并可见皮层区异常强化。

  • These findings presumably reflect postictal changes induced by seizure.

    这些表现可能与癫痫发作后的改变有关。

DDx
  • Limbic encephalitis

    边缘性脑炎

  • Hypoglycemia and other toxic-metabolic etiologies

    低血糖或其他毒性-代谢性病变

  • Heat stroke

    中暑

  • Ischemia, including transient global amnesia

    局部缺血,包括一过性完全遗忘症

  • Venous sinus thrombosis

    静脉窦血栓形成


Rx

Medical management according to seizures etiology

针对癫痫病因药物治疗