Postdoc Positions Focusing on the Roles of RNA m5C Regulation in Normal
and Malignant Hematopoiesis
Postdoctoral positions are available in the research laboratories of Dr. Mingjiang Xu (https://directory.uthscsa.edu/academics/profile/xum1) at University of Texas Health San Antonio and Dr. Chuan He (https://he-group.uchicago.edu) at University of Chicago. The candidate will carry collaborative projects between the Xu and the He labs to investigate the roles of RNA m5C in the regulation of hematopoietic stem/progenitor cell function and in the development of hematological malignancies. These studies will be the extension of a recent discovery by the He and Xu labs published in Nature
(https://www.nature.com/articles/s41586-024-07969-x). The candidate will define the impact of RNA m5C marks on the regulation of a diverse physiological and pathological processes including transcription, translation, aging and transformation, focusing on the hematopoietic system. The unique tools are ranging from m5C writers/erasers/reader modulations and m5C profiling to animal modeling and primary human sample testing.