胸外科医师协会 (STS) 关于寡转移性非小细胞肺癌外科治疗的临床实践指南

局部联合治疗 (LCT) 在寡转移性非小细胞肺癌 (NSCLC) 患者中的应用正在迅速发展，大多数数据支持这种治疗方法的益处，包括肺切除术用于适当选择的候选者。然而，实践在机构和区域上差异很大，缺乏以证据为基础的指南。

The Society of Thoracic Surgeons assembled a panel of thoracic surgical oncologists to evaluate and synthesize the available evidence regarding the role of pulmonary resection as LCT. Clinical and research questions of interest were identified, and a complete literature review was conducted. Best practice guidelines were developed accordingly.

胸外科医师协会组建了一个胸外科肿瘤学家小组，以评价和整合关于肺切除术作为 LCT 作用的现有证据。确定了感兴趣的临床和研究问题，并进行了完整的文献综述。相应地制定了最佳实践指南。

The panel identified 7 areas of controversy, and data were assimilated to support the best recommended practices related to these clinical issues. Ultimately, a number of issues in this realm were found to have a high level of evidence to support the role for surgical therapy in patients with stage IV lung cancer. However, the nuances of how these operations are conducted remain in equipoise, without ample evidence to support the extent of resection or nodal dissection.

专家小组确定了7个有争议的领域，并对数据进行了汇总，以支持与这些临床问题相关的最佳推荐实践。最终，发现这一领域的一些问题具有高水平的证据支持手术治疗在 IV 期肺癌患者中的作用。然而，如何进行这些手术的细微差别仍然是平衡的，没有足够的证据支持切除或淋巴结清扫的范围。

Clear data exist to support the use of surgical resection of the primary lung tumor as LCT in stage IV lung cancer. Evidence-based recommendations have been provided to guide multidisciplinary teams on the implementation of treatment plans as well as to guide researchers on areas of ongoing need for further investigation.

存在明确的数据支持在 IV 期肺癌中使用手术切除原发性肺肿瘤作为LCT。提供了基于证据的建议，以指导多学科小组实施治疗计划，并指导研究人员持续需要进一步研究的领域。