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About the Lab:
The Sun lab focuses on the function of cilia and the etiology of ciliopathies, particularly polycystic kidney disease and primary ciliary dyskinesia. Originally established as a zebrafish lab, the Sun lab has expanded into mouse and cell culture to translate novel findings to clinically more relevant systems. Our interdisciplinary research has taken us into fields that span genetics, chemical genetics, biochemistry, developmental biology, and imaging. More details can be found at https://medicine.yale.edu/profile/zhaoxia-sun/ and https://www.sun-lab-yale.org/. Current key questions include tissue-specific functions of cilia in epithelial cyst formation and interstitial fibrosis in the kidney, the building of motile cilia in zebrafish and the mammalian airway, and chemical-genetic interactions in zebrafish ciliopathy models.
Qualifications:
The applicant should hold a PhD in biological sciences. Proficiency in molecular, cellular biology and mouse genetics is a must. We expect the candidate capable of logical reasoning and robust experimental design and execution.
The ideal applicant will be responsible, self-motivated and able to take on initiatives while working independently and in a team environment. We expect the candidate to be open-minded and ready to learn novel approaches, adjust to new environment, and explore all the opportunities available in our vibrant research community.